The effects of graded motor imagery and its components on chronic pain: A systematic review and meta-analysis

This is the post-print version of the final paper published in The Journal of Pain. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. Copyright @ 2013 The American Pain Society.Graded motor imagery (GMI) is becoming increasingly used in the treatment of chronic pain conditions. The objective of this systematic review was to synthesize all evidence concerning the effects of GMI and its constituent components on chronic pain. Systematic searches were conducted in 10 electronic databases. All randomized controlled trials (RCTs) of GMI, left/right judgment training, motor imagery, and mirror therapy used as a treatment for chronic pain were included. Methodological quality was assessed using the Cochrane risk of bias tool. Six RCTs met our inclusion criteria, and the methodological quality was generally low. No effect was seen for left/right judgment training, and conflicting results were found for motor imagery used as stand-alone techniques, but positive effects were observed for both mirror therapy and GMI. A meta-analysis of GMI versus usual physiotherapy care favored GMI in reducing pain (2 studies, n = 63; effect size, 1.06 [95% confidence interval, .41, 1.71]; heterogeneity, I2 = 15%). Our results suggest that GMI and mirror therapy alone may be effective, although this conclusion is based on limited evidence. Further rigorous studies are needed to investigate the effects of GMI and its components on a wider chronic pain population.NHMR

A Two-stage approach to harmonic rejection mixing using blind interference cancelling

Current analog harmonic rejection mixers typically provide 30–40 dB of harmonic rejection, which is often not sufficient. We present a mixed analog-digital approach to harmonic rejection mixing that uses a digital interference canceler to reject the strongest interferer. Simulations indicate that, given a practical RF scenario, the digital canceler is able to improve the signal-to-interference ratio by 30–45 dB

Experimental Verification of a Harmonic-Rejection Mixing Concept using Blind Interference Canceling

Abstract—This paper presents the first practical experiments\ud on a harmonic rejection downconverter, which offers up to 75 dB of harmonic rejection, without an RF filter. The downconverter uses a two-stage approach; the first stage is an analog multipath/ multi-phase harmonic rejection mixer followed by a second stage providing additional harmonic rejection based on blind adaptive interference canceling in the discrete-time domain. The aim is to show its functional operation and to find practical performance limitations. Measurement results show that the harmonic rejection of the downconverter is insensitive to frontend nonlinearities and LO phase noise. The canceler cannot cope with DC offsets. The DC offsets are removed by highpass filters. The signal paths used to obtain an estimate of the interference must\ud be designed to provide as much attenuation of the desired signal as possible

A Blind Interference Canceling Technique for Two-Stage Harmonic Rejection in Down-mixers

This paper presents practical experiments on a harmonic rejection down-mixer, which offers up to 75 dB of harmonic rejection, without an RF filter. The down-mixer uses a two-stage approach; the first stage is an analog multi-path/multiphase harmonic rejection mixer followed by a second stage providing additional harmonic rejection based on blind adaptive interference canceling in the discrete-time domain. The aim is to show its functional operation. The canceler cannot cope with DC offsets. The DC offsets are removed by highpass filters. The signal paths used to obtain an estimate of the interference must be designed to provide as much attenuation of the desired signal as possible. Front-end nonlinearities and DC offsets are discussed

The Long-term Coercive Effect of State Community Benefit Laws on Hospital Community Health Orientation

This study is an examination of the long-term coercive effect of state community benefit laws (CB Laws) on the provision of community health activities in U.S. acute care hospitals. The sample included all the not-for-profit and investor owned acute care hospitals for which 1994 and 2006 AHA Annual Survey data were available. A panel design was used to longitudinally examine the effect that state CB Laws had on hospital community health orientation activities and the provision of health promotion services, after controlling for the influence of other organizational and environmental variables that might affect these activities and services. The authors found that both CB Law state and non CB Law state hospitals increased their number of orientation activities and promotion services from 1994 to 2006. However, there was no significant difference in the gains in these activities and services between these two groups of hospitals. These results suggest that other environmental and organizational factors may mediate the effect of the state CB Laws over time

Aerodynamic loads on deployed canard surfaces and rocket nose section of the Apollo launch escape vehicle

Aerodynamic loads on deployed canard surfaces and rocket nose section of Apollo launch escape vehicl

Wind-tunnel investigation of the aerodynamic pressures on the Apollo command module configuration

Wind tunnel study of aerodynamic pressures on Apollo command module configuratio

Upcoming planetary missions and the applicability of high temperature superconductor bolometers

Planetary missions to Mars and beyond can last 11 years and longer, making impractical the use of stored cryogens. Passive radiative coolers and single-stage mechanical coolers remain possibilities. CRAF and CASSINI, both using the newly developed Mariner Mark 2 spacecraft, will be the next outer planet missions after Galileo; they are intended to provide information on the origin and evolution of the solar system. CRAF is a cometary rendezvous mission slated for a 1994 launch. CASSINI has been chosen by ESA and will be launched by a Titan 4/Centaur in 1996. It will fly by Jupiter in 2000, inject an ESA-supplied probe into Titan in 2002, and take data in Saturn orbit from 2002 to 2006. NASA/Goddard is currently developing a prototype Fourier transform spectrometer (CIRS) that will be proposed for the CASSINI mission. The baseline infrared detectors for CIRS are HgCdTe to 16 microns and Schwarz-type thermopiles from 16 to 1000 microns. The far infrared focal plane could be switched from thermopiles to high temperature superconductor (HTS) bolometers between now and 1996. An HTS bolometer could be built using the kinetic inductance effect, or the sharp resistance change at the transition. The transition-edge bolometer is more straightforward to implement and initial efforts at NASA/Goddard are directed to that device. A working device was made and tested in early 1989. It also has somewhat elevated noise levels below 100 Hz. Upcoming efforts will center on reducing the time constant of the HTS bolometer by attempting to deposit an HTS film on a diamond substrate, and by thinning SrTiO3 substrates. Attempts will be made to improve the film quality to reduce th 1/f noise level, and to improve the thermal isolation to increase the bolometer sensitivity. An attempt is being made to deposit good-quality HTS films on diamond films using an MOCVD technique

Swine management : preventing diseases

"Many outbreaks of disease in swine herds can be avoided by using management practices directed at disease prevention. Disease control is only one facet of a successful management program."--First page.B.L. Moseley (School of Veterinary Medicine)Revised 2/84/5

An Expanded View of the Eukaryotic Cytoskeleton

A rich and ongoing history of cell biology research has defined the major polymer systems of the eukaryotic cytoskeleton. Recent studies have identified additional proteins that form filamentous structures in cells and can self-assemble into linear polymers when purified. This suggests that the eukaryotic cytoskeleton is an even more complex system than previously considered. In this essay, I examine the case for an expanded definition of the eukaryotic cytoskeleton and present a series of challenges for future work in this area